Chlorpromazine versus penfluridol for schizophrenia
نویسندگان
چکیده
منابع مشابه
Penfluridol for schizophrenia.
BACKGROUND Penfluridol, available since 1970, is an unusual long acting oral antipsychotic agent for the treatment of schizophrenia. It may be considered a depot medication as it is administered once a week. OBJECTIVES To review the effects of penfluridol for treatment of those with schizophrenia and schizophrenia-like illnesses in comparison to placebo, other antipsychotic medication or no i...
متن کاملPenfluridol Maintenance Therapy in Schizophrenia: a Controlled Study
Twenty eight chronic schizophrenics were assigned in a double blind fashion to treatment with penfluridol or placebo for a period of 12 weeks. The clinical picture including the side effects were monitored regularly, whenever the clinical picture deteriorated haloperidol in individually adjusted doses was added to the treatment regimen. By the end of the study 12 out of the 14 placebo patients ...
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OBJECTIVE To establish whether there is any difference in the efficacy of a chlorpromazine regimen and a sumatriptan regimen for the management of the pain of acute severe migraine. SETTING Two urban teaching hospital emergency departments. METHODS Prospective, randomised, unblinded, crossover trial. All patients received intravenous metoclopramide 10 mg and 1000 ml of normal saline over 1 ...
متن کاملClozapine v. chlorpromazine in treatment-naive first-episode schizophrenia.
BACKGROUND The differential effects of so-called 'first- and second generation' antipsychotic medications, when given in the first episode, on the long-term outcome of schizophrenia remain to be elucidated. AIMS We compared the 9-year outcomes of individuals initially randomised to clozapine or chlorpromazine. METHOD One-hundred and sixty individuals with treatment-naive, first episode schi...
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OBJECTIVE The purpose of this study was to compare the efficacy of olanzapine with that of chlorpromazine plus benztropine in patients with treatment-resistant schizophrenia. METHOD One hundred three previously treatment-resistant patients with schizophrenia diagnosed according to the DSM-III-R criteria were given a prospective 6-week trial of 10-40 mg/day of haloperidol. Eighty-four of them ...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2017
ISSN: 1465-1858
DOI: 10.1002/14651858.cd011831.pub2